黑帮老大艾迪?金策划了一起凶杀案，被偶然路过的年轻人西恩?琼斯（Nathan Phillips 饰）目击。为了在法庭上成功指控这个作恶多端的黑社会头子，警方派出资深联邦密探尼维利?费恩（Samuel L. Jackson 饰）负责保护西恩，并将其从夏威夷护送至洛杉矶法庭。为避免证人遇害，尼维利采取声东击西的策略，与西恩偷偷乘上一架普通的红眼航班。
然而这项绝密的计划被艾迪安排在警方的内奸获知，为了逃脱法律制裁，艾迪派出携带大量毒蛇的杀手登上飞机，一场离奇恐怖的血腥灭口案件就此展开……
In the British countryside, the Harver family head out on an idyllic summer camping trip where they can bury past tensions and enjoy some family bonding. But when their camp is sabotaged by an unseen intruder in the night, they head to the nearby creepy old farm desperate for help, where vengeful farmer Hunt Hansen and his hideously deformed son aren't farming animals... Caged and waiting for their limbs to be severed, cooked and eaten one at a time, the Harver family must overcome their differences and unite in order to escape alive!@
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